R & D Programmes
Introduction
The Centre of Applied Science for Health (CASH) builds on long-standing collaborations between science researchers at ITT Dublin (ITT Dublin), the National Institute for Cellular Biotechnology at Dublin City University (NICB-DCU), chemistry and biology researchers at the National University of Ireland Maynooth (NUI Maynooth), and the Adelaide & Meath Hospital incorporating the National Childrens Hospital (AMNCH / Tallaght Hospital).
The Centres multi-disciplinary research teams are to the forefront of new and exciting studies crossing the traditional boundaries of biology, chemistry and engineering. Specific areas of investigation include:-
- Studies of the microbial host interaction
Examining the processes of microbial adhesion and infection into human tissues with the objective of identifying the critical molecules and/or mechanisms with a view to the creation of more detailed understandings, and the development of novel methods of intervention. Allied to this are the development of novel antimicrobial compounds (natural and synthetic) as possible antibiotics and the creation of novel polymeric surface coatings with anti-microbial properties. - Biomedical devices
This area brings together, chemists, engineers and clinicians focused on the creation and translation of new knowledge and technologies into the medical arena. Key target areas for study are in the areas of thin-film microsensor design and fabrication focused on ex vivo measurements of cardiac markers of hypertension, neurological oxidative stress, and in vivo studies and diagnoses of physical dynamic processes of the human gastrointestinal tract. - Translational research in cancer and other diseases
Including use of sophisticated proteomic, mRNA/miRNA protein expression profiles to aid the early detection, warning of recurrence, and monitoring of responses to cancer, and translational platelet science studies in patients with asymptomatic carotid stenosis and ischaemic cerebrovascular disease.
